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Barrington James
Associate Medical DirectorBarrington James • Liverpool, Merseyside, United Kingdom
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Associate Medical Director

Associate Medical Director

Barrington James • Liverpool, Merseyside, United Kingdom
15 days ago
Job type
  • Full-time
Job description

Job Description

Associate Medical Director – Site Network (UK)



All candidates should make sure to read the following job description and information carefully before applying.


60% Principal Investigator (PI) Work / 40% Operations & Site Growth



Role Overview


We are seeking a clinically active Associate Medical Director to join a growing UK clinical site network. This hybrid role combines hands-on Principal Investigator (PI) leadership (60%) with strategic operational and site expansion responsibilities (40%).


You will play a key role in driving high-quality clinical trial delivery, ensuring patient safety, scientific integrity, and regulatory compliance, while also supporting the growth, performance, and scalability of the site network across the UK.



Key Responsibilities


Principal Investigator / Clinical Delivery (60%)



  • Act as Principal Investigator (PI) on assigned interventional clinical trials across multiple therapeutic areas (with emphasis on oncology, haematology, and complex chronic disease studies where applicable)


Ensure full compliance with ICH-GCP, UK regulatory requirements, and study protocols


Oversee patient eligibility, informed consent, safety oversight, and medical decision-making


Provide medical leadership on protocol feasibility, amendments, and study conduct


Lead investigator oversight visits, sponsor interactions, and audit/inspection readiness


Support and mentor sub-investigators and site clinicians to maintain high-quality delivery




Site Operations & Growth (40%)



  • Support expansion of the UK site network footprint, including identification of new site opportunities


Contribute to site start-up strategy, feasibility assessments, and pipeline prioritisation


Work closely with operations teams to improve recruitment performance, activation timelines, and retention


Build and maintain relationships with sponsors, CROs, and strategic partners


Support development of standardised processes across sites to improve efficiency and quality


Provide clinical input into business development proposals and feasibility pipelines


Help shape the medical and operational strategy of the network




Key Requirements



  • GMC-registered physician with active licence to practise in the UK


Strong background in clinical trials (industry or academic setting)


Prior experience as Principal Investigator (PI) or Sub-Investigator


Solid xwwtmva understanding of ICH-GCP, MHRA expectations, and clinical research governance


Demonstrated ability to balance clinical responsibility with operational leadership


Excellent communication skills with ability to engage investigators, sponsors, and internal teams


Strong organisational and decision-making capability in fast-paced environments




What This Role Offers



  • Hybrid role combining hands-on patient-facing PI work with strategic leadership


Opportunity to shape and scale a rapidly growing UK site network


Direct impact on trial delivery performance and patient access to innovation


High visibility role with influence across clinical operations and business growth


Collaborative environment with strong focus on quality and scientific integrity



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Associate Medical Director • Liverpool, Merseyside, United Kingdom

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