Talent.com
Idibu
Senior Principal Scientist, In Vitro ModelsIdibu • Oxford, England, UK
Senior Principal Scientist, In Vitro Models

Senior Principal Scientist, In Vitro Models

Idibu • Oxford, England, UK
14 days ago
Salary
£60,000.00 yearly
Job type
  • Full-time
Job description
Senior / Principal Scientist In Vitro Models

Oxford On-site Start-up Biotechnology Company

Talentmark is partnering with a biotech start-up developing next-generation gene therapies for severe genetic diseases. With a highly collaborative scientific team and innovative platform technologies the company is advancing cutting-edge preclinical programmes focused on delivering transformative therapies to patients with high unmet need.

This is an exciting opportunity for a talented scientist to play a key role in establishing advanced in vitro models that support the discovery and optimisation of novel gene therapy vectors. Working within a highly collaborative research team youll help develop physiologically relevant models that accelerate the translation of cutting-edge science into life-changing therapies. This opportunity is available at Senior Scientist or Principal Scientist level depending on your experience and technical expertise.

The Role:

 As a Senior or Principal Scientist youll lead the development of complex in vitro systems including 3D cultures co-cultures organoids and organ-on-a-chip platforms with a particular focus on generating robust models to evaluate gene therapy vector is a predominantly hands-on laboratory position.

Responsibilities:
  • Design establish and optimise advanced in vitro models including 3D cultures organoids co-cultures and organ-on-a-chip systems.
  • Develop physiologically relevant tissue models using primary cells with a particular interest in kidney biology.
  • Design and execute assays to assess vector transduction transgene expression and safety.
  • Generate analyse and interpret complex biological datasets to support research decisions.
  • Work closely with multidisciplinary teams across vector engineering in vivo research and delivery technologies.
  • Maintain high laboratory standards and contribute to multiple research programmes simultaneously.
Your Background:
  • PhD in a relevant life sciences discipline and bring industry experience within biotechnology pharmaceuticals or translational research environments.
  • Proven experience developing complex in vitro cell culture models (3D cultures organoids and/or co-cultures).
  • Strong hands-on mammalian cell culture experience including primary cells.
  • Excellent molecular and cellular biology laboratory skills.
  • Experience analysing complex biological data.
Highly Desirable
  • Experience developing organ-on-a-chip or microphysiological systems.
  • Primary kidney cell culture or renal model experience.
  • Gene therapy viral vector or advanced therapeutics experience.
If youre passionate about developing advanced in vitro models and want to contribute to pioneering gene therapy research with real patient impact wed love to hear from you.

Why Apply
  • Help develop next-generation gene therapies that have the potential to transform the lives of patients with genetic diseases.
  • Lead cutting-edge research using advanced in vitro models including organoids 3D cultures and organ-on-a-chip technologies.
  • Join a collaborative venture-backed biotech where youll work alongside expert scientists and have a direct impact on research and innovation.
  • Bonus private healthcare insurance life insurance and an equity options scheme
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference 196 300 in all correspondence.
Employment Type : Full Time
Experience: years
Vacancy: 1
Yearly Salary Salary: £ 60000 - 75000
Create a job alert for this search

Senior Principal Scientist, In Vitro Models • Oxford, England, UK

Similar jobs

Senior Scientist

Genomics plcOxford, England, GB
Full-time

The growth of Genomics is partnered with the personal growth of our people.We ensure that all employees have the tools, technologies, benefits, and support systems to develop and flourish.We offer ... Show more

 • Promoted

Senior NGS Scientist — Genomics Innovation, Oxford

Java Script WorksOxford, England, GB
Full-time

Senior Scientist (Next-generation sequencing) - Generative Biology Institute.This is a job posted by our partner Jooble.To read the full text, please click on the "Apply Now" link.In bioinformatics... Show more

 • Promoted

Lead Quantum Scientist - Superconducting Circuits & Scaling

UKRIHarwell, England, GB
Full-time

UKRI's National Quantum Computing Centre at the Harwell Campus in Oxfordshire seeks a Staff Quantum Scientist (Superconducting Circuits) to lead on scalable quantum hardware projects and to develop... Show more

 • Promoted

Senior Scientist, Biotechnology - Pathogen

Ellison Institute of Technology OxfordOxford, England, GB
Full-time

At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact.We bring together visionary scientists, technologists, engineers, researche... Show more

 • Promoted

Senior Scientist I – Biocompatibility

Abbott LaboratoriesWitney, England, GB
Full-time

Senior Scientist I – Biocompatibility.Bring your passion, ideas, and purpose to life in a company that can truly help you achieve your full potential.Known globally for the development of revolutio... Show more

 • Promoted

Senior Scientist

GenomicsOxford, England, GB
Full-time

Genomics is a science‑led transatlantic TechBio combining large‑scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare... Show more

 • Promoted

Senior Scientist, Analytical Development & GMP

Replimune-2Abingdon, England, GB
Full-time

Scientist Analytical Development at Milton Park to lead development, qualification and validation of analytical methods for drug substance and product from preclinical through late‑phase clinical d... Show more

 • Promoted

Senior Machine Learning Scientist

Aioi Nissay Dowa EuropeOxford, England, GB
Permanent

The role will support the development of a privacy-preserving generative AI ecosystem designed to protect personal and sensitive corporate data by design, including data residency, anonymisation an... Show more

 • Promoted

Principal Scientist, Immunogenicity and Ligand Binding Assays

Moderna TherapeuticsOxford, England, GB
Full-time

Principal Scientist, Immunogenicity and Ligand Binding AssaysApplylocations: Oxford - England: Clinical Developmenttime type: Full timeposted on: Posted Todayjob requisition id: R19340**T... Show more

 • Promoted

Senior AFM Applications Scientist (UK) – Semiconductor Metrology

InfinitesimaAbingdon, England, GB
Full-time

Would you like to be instrumental in enabling the next generation of semi-conductors? As a.You’re working across the full product lifecycle, shaping how our solutions perform in the field and how t... Show more

 • Promoted

Senior Computational Genomics Scientist – Pathogen

JobtailorOxford, England, GB
Full-time

At EIT we are seeking an experienced and detail oriented.Senior or Non Senior Scientist.This is an exciting opportunity to develop novel computational approaches for microbial data that will become... Show more

 • Promoted

Scientist

NorthreachOxford, England, GB
Full-time

Get AI-powered advice on this job and more exclusive features.This range is provided by Northreach.Your actual pay will be based on your skills and experience — talk with your recruiter to learn mo... Show more

 • Promoted

Director, Life Sciences (Health and Life Sciences)

WSP in the UK & IrelandAbingdon, England, United Kingdom
Full-time

What if you could do the kind of work the world needs? At WSP, you can access our global scale, contribute to landmark projects and connect with the brightest minds in your field to do the best wor... Show more

 • Promoted

Junior Research Scientist: Sustainable SAP Polymers

A&B Smart MaterialsOxford, England, GB
Full-time

A sustainable materials company in Oxford is seeking a Junior Research Scientist to develop biodegradable superabsorbent polymers.The ideal candidate holds a PhD in Polymer Chemistry and has a pass... Show more

 • Promoted

Scientist II

Oxford Gene TechnologyOxford, England, GB
Full-time

OGT is a leading global provider of clinical and diagnostic genomic solutions.We believe in creating products and partnerships that enable clinicians to deliver personalised healthcare to patients ... Show more

 • Promoted

Senior Quantum Scientist: Superconducting Circuits

STFCHarwell, England, GB
Permanent

The National Quantum Computing Centre (NQCC) at Rutherford Appleton Laboratory, Harwell Campus, Oxfordshire, UK, operated by STFC, seeks a Staff Quantum Scientist (Superconducting Circuits) on a pe... Show more

 • Promoted

Senior Scientist, Biotechnology - Pathogen

Ellison Institute of TechnologyOxford, England, GB
Full-time

At the Ellison Institute of Technology (EIT), we're on a mission to translate scientific discovery into real world impact.We bring together visionary scientists, technologists, engineers, researche... Show more

 • Promoted

Research Associate in In Vitro Models of Early Development (10402)

Rosalind Franklin InstituteHarwell, England, GB
Full-time +1

The Rosalind Franklin Institute (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in ... Show more

 • Promoted

Oligonucleotide Synthesis Scientist – On-site R&D Lead

Oxford Nanopore TechnologiesOxford, England, GB
Full-time

Oxford Nanopore Technologies is seeking a highly motivated Oligonucleotide Scientist to join our Oligonucleotide Synthesis Team in Harwell, Oxfordshire.In this fully on-site position, you will deve... Show more

 • Promoted

Principal Scientist, Bioanalytical & Molecular Assays

BioSpaceOxford, England, GB
Full-time

Joining Moderna means advancing mRNA science to transform medicine.Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.This role is b... Show more