Interim MS&T Scientist (12 Month FTC)

The purpose of this role is to support the introduction optimisation and delivery of new processes within the CGT Catapult Manufacturing Innovation Centres (MICs). The MS&T (Manufacturing Science and Technology) Scientist contribute to new product introduction technology transfer and GMP manufacturing across Cell Therapy and Viral Gene Therapy processes and aligned modalities.

Key Responsibilities

• Provide technical expertise in a recognised modality with a broad understanding of aligned technologies
• Apply in-depth knowledge of process engineering aseptic handling molecular biology biochemistry and/or purification techniques to evaluate and optimise cell and gene therapy methodologies to support technology transfer of robust and scalable manufacturing processes
• Execute hands-on developmental or scale-up runs associated with the establishment of new processes within CGT Catapult
• Support the creation and execution of technology transfer project plans for the introduction of new processes to the CGT Catapult MICs in Stevenage and Braintree
• Collaborate with Scale Enabling Technology (SET) Quality and project teams across the CGT Catapult
• Facilitate collaboration with therapy/technology developers CMOs and CROs both at the CGT Catapult MICs and by offsite working
• Ensure documentation compliance with onsite QMS and HSE
• Author and review new GMP procedures and batch related documentation for the CGT Catapult MICs
• Produce project reports and present progress against project deliverables
• Deputise for the MS&T Senior Scientist(s) as required representing CGT Catapult in technical collaborations

Experience:

• Demonstrable academic or industrial experience in a process development and/or GMP manufacturing setting (essential)
• Demonstrable experience in two or more cell and gene based therapy methodologies e.g. mammalian/primary cell culture single-use stirred tank reactor (STR) operation chromatography tangential flow filtration (TFF) and/or normal flow filtration continuous centrifugation aseptic handling including tube welding and sealing etc. (essential)
• Demonstrable experience of working within either the biotech biopharma CMO CRO or other types of commercial-facing organisations (desirable)
• Demonstrable experience of the Quality by Design (QbD) approach to product development (desirable)
• Demonstrable experience of working to commercial timelines and within budget (desirable)

Skills Knowledge and Expertise

• Highly motivated pragmatic and practical to support the mission of the Cell and Gene Therapy Catapult to accelerate the development of a commercial cell and gene-based therapy industry in the UK
• Desire to establish a high-profile career within cell and gene sector and the personal drive to help push the sector to be a commercial success
• Proven knowledge of cutting-edge solutions to address challenges of scalability and enclosed disposable systems
• Excellent interpersonal verbal and written communication skills (including presentation skills)
• Ability to quickly establish credibility and build rapport and trust
• Proven ability to engage constructively with colleagues at all levels across different departments to deliver objectives and to respond to a wide range of Collaborator and management needs
• Ambitious collaborative driven
• A good team player with a hands-on approach and adaptable to new challenges
• Flexible and pragmatic able to learn quickly and respond flexibly to project needs and priorities
• Flexibility towards work assignments and new learning
• Resilient with the ability to manage multiple and varied tasks and prioritise workload within a fast-paced professional environment with a strong attention to detail
• A roll your sleeves up hands-on attitude towards varying work assignments
• Comfortable operating autonomously once goals and objectives are set
• Ability to work well under pressure and to be able to take the initiative when completing tasks to deliver objectives and to respond to a wide range of Collaborator and management needs
• Proficient in Microsoft 365 applications with strong IT data management and presentation skills
• A positive attitude towards learning personal and professional development
• Keeps up to date with professional knowledge expertise and best practice
• Willingness to travel as required by the role

Education / Qualifications:

• Educated to a degree level within a Life Science subject

Required Experience:

Contract

Employment Type : Contract
Experience: years
Vacancy: 1