Research Physician RWEEpidemiology

Job Title: Research Physician - RWE/Epidemiology

Location: London Bridge SE1

Term:Full-Time Permanent

Salary:Competitive Benefits (Private Medical Private Dental Pension25 days Annual leave plus bank holidays& Many more)

Richmond Pharmacology are an early phase Clinical Research Organisation (CRO) where we are conducting pioneering early phase healthy participants and patient participant trials. Our experienced and world-renowned team our central London location and our global reach contribute to making Richmond Pharmacology an exciting and dynamic place to work.

Purpose of the job

This is an excellent opportunity for a clinically trained physician to combine medicalexpertisewith real-world evidence (RWE) science in a dynamic growing team.Reporting directly to the Medical Director you willbe responsible forthe day-to-day scientific and clinical delivery of observational studies patient registries and AI-assisted datainsights that generate evidence for our clients.

You will work closely with the Medical Director on study design taking ownership of delivery documentation and stakeholder coordination across projects. The primary focus of the role is non-interventional research and registry work with a smaller proportion of time supporting interventional clinical trials as needed. This is a hands-on scientific role with clear scope to develop yourexpertisein RWEmethodology health data science and evidence generation.

Main duties and responsibilities

Study Design & Oversight

• Provideclinicalinput in thedesign of real-world evidence studiesincluding retrospective cohort studies case-control studiesdatabase studiespatient registries and longitudinal observational cohorts.
• Ensuresufficient patientsto support theobjectivesof allNISstudies.
• Provide medical support fornon-interventional studies ensuring compliance with UK regulations ICH-GCP (where applicable) and GDPR.
• Oversee medical components of AI-assisted studiesAI-assisted data lake searchesmodel validation algorithmic bias review and clinical input into machine learning outputs.
• Be themain liaison tothePrincipal Investigator; in consultationwith PI make decisions to include/reject participants based on protocolseligibility criteriaclinical practice unit guidelines.Escalate complex issues to the Medical Director/PI as needed.
• Collaboratein planning and design of screening activities with other departmentsto achieve study timelinese.g.Patient Engagement Team andRecruitment

This role mayalsoinvolve supporting interventional trial activityincluding:

• Providing medical oversight and clinical input on assigned interventional studies working alongside the Principal Investigator project managementclinical operations teamvolunteerrecruitmentand patient engagement teamsto support trial delivery.
• Contributing to protocol review eligibility assessments and medical monitoring activities as.
• Supporting the preparation of trial documentation including clinical sections of protocols investigator brochures and safety reports.
• Ensuring compliance with ICH-GCP applicable regulations and sponsor requirements for any assigned interventional work.

Epidemiological & Analytical Contributions

• Providesupport for the creation andclinical interpretation of epidemiological data outputsincluding incidence prevalence risk factor modelling and survival analyses.
• Guide the development of disease definitions cohort selection algorithms and clinical phenotypes for use in large datasets.
• Review and approvedata handling plans (DHPs) andstatisticalanalysis plans (SAPs) from a clinical perspective to ensure scientific rigor and relevance.

Medical Writing & Regulatory

• Contribute to or review scientific documents such as:
• Study protocols
• Statistical analysis plans (SAPs)
• SOM sections for GLSO
• PIS/ICF sections
• Clinical Study Reports (CSRs) and RWE publications
• Regulatory submissions
• Medical Review Summaries.
• Attend REC meetings and present study applicationsunder the direction of the Medical Director.
• Support dissemination of findings through white papers presentations and peer-reviewed publications.
• Take ownership of SOPs/WIs andbe responsible formaintainingtheir status and updates
• Prepare presentations for prospective sponsors on study proposals e.g.bid defence

Skills and Experience:

• Medical Degree (MBBS MBChB MD or equivalent)
• Full GMC Registration
• Postgraduate Clinical Training
  
• Postgraduate Qualification in Epidemiology Public Health or Clinical Research (Desirable)
• Training in Real-World Evidence (RWE) Methodologies (Desirable)
• Good understanding of internal and external real-world data sources (private and public).
• Comfortable interpreting and critically evaluating biostatistical results and methodologies.

Application:

If you are interested in the role please register your details including a copy of your CV. Please note while we try to respond to every candidate the high volume of applications anticipated may make this impossible and we ask for your patience and understanding.

Required Experience:

IC

Employment Type : Full-Time
Experience: years
Vacancy: 1