Translational Medicine Expert – Dermatology, Associate Director

Salary Range:

67900.00 - 126100.00

Job Description Summary

#LI-Hybrid
Location: Westworks London UK

As a Translational Medicine Expert (TME) you will provide medical and scientific expertise and leadership to:
Drive success of early global programs develop and implement strategies to achieve Transition Decision Point (TDP)
Drive success of late global programs by developing and implementing strategies which lead to clinical pharmacology and profiling packages that meet regulatory requirements and support differentiated and competitive drug labeling.
Support Translational Research in developing new indications endpoints and biomarkers using in vitro in vivo or in silico methods.
Provide scientific expert assessments and support for in-licensing opportunities including due diligences.

Job Description

Key Responsibilities:

Early clinical projects (Phase I / II Discovery):

Develop in collaboration with the dermatology TA and work with teams to carry out strategies for the Translational Medicine component of drug development projects from Research to TDP in single or multiple indications including post-indication expansion (PIE) projects.

Late-stage clinical projects (post-TDP Profiling):

In collaboration with the dermatology TA Head: Act as a key leader in developing the Ph2-3 and post-approval profiling strategy for drug programs representing TMDP on Global Project Team (GPT) along with other TM line functions. Provide support for dose selection study design and other clinical pharmacology matters throughout the development cycle. Oversee conduct and interpretation of studies prioritized by the to support the pivotal trials such as special populations drug-drug interactions mechanism of action assessments Pediatric Investigational Plan etc.

Translational Research (TR; indication seeking endpoint and biomarker development):

In collaboration with the dermatology TA Head BR Research scientists other TM line functions (BMD CS&I PCS PKS) develop strategies to identify initial or expansion (PIE) indications and to obtain sufficient evidence to fund these ideas.

Business Development and Licensing (BD&L; in-licensing and out licensing compounds):

Participate on BD&L teams as the TM representative.

General responsibilities:

• Responsible for clinical monitoring and integrated safety data review during and after the live phase of a study.

• Provides medical and scientific leadership and expertise to all line functions on the study team.

• Represent clinical Translational Medicine aspects to Health Authorities and other stakeholders (e.g. payers patient advocacy groups).

• Oversee publication strategy for TM studies; lead writing of scientific publications; present study results externally where appropriate

Leadership:

• Lead study-specific teams/ clinical trial teams in partnership with other line functions.

• Lead BR-sub-team(s) on Global Project Teams for late-phase programs

• Collaborate closely with other TM (especially CS&I) and non-TM (especially Project Management) line functions to ensure operational excellence continued urgency and close attention to timelines costs and subject burden in balance with high scientific standards and innovation

Essential Requirements:

• Doctoral degree MD

• Board certified Dermatologist

• Preferably Ph.D. within dermatology/immunology

• At least 5 years experience in a pharmaceutical/biotech company CRO or academic medical center or related experience

• Innovation: Seeks out new clinical discovery opportunities and approaches to reach TDP

• Recognized expert in field driving success for individual studies and projects; respected by colleagues across R&D Development and externally

• Fluent oral and written English

Benefits & Rewards

At Novartis were committed to reimagining medicine together - and rewarding the people who make it happen.

Expected Annual Base Salary Range for role:67900.00 - 126100.00

The base salary offered is determined based on gender-neutral objectives such as relevant skills competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.

In addition to your base salary you may be eligible for a performance-based bonus depending on certain performance parameters.

The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally such as insurance plans retirement plans wellbeing resources and global recognition addition we provide flexible and hybrid working options where possible and minimum 14 weeks paid parental leave.

In addition to your base salary you may be eligible for a performance-based bonus depending on certain performance -term equity awards granted at group level may also be part of your package. Further details will be provided during the application process.

You may be eligible for a company vehicle or a car allowance in accordance with the applicable local Novartis policies and guidelines.

Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse equitable and inclusive environment that treats all employees with dignity and respect as outlined in our Code of Ethics.

Read our brochure to learn more about our global total rewards offering:

Benefits and compensation may vary by country and are subject to local legal requirements including provisions of collective bargaining agreements where applicable. A full overview of your compensation package including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity will be communicated separately to you during the application process.

Commitment to Diversity and Inclusion / EEO

Novartis is committed to building an outstanding inclusive work environment and diverseteamsrepresentative of the patients and communities we serve.

Skills Desired

Clinical Trials Cross-Functional Teams Data Analysis Data Monitoring Drug Development Drug Discovery Medical Research Medical Strategy People Management

Required Experience:

Director

Employment Type : Full-Time
Experience: years
Vacancy: 1
Monthly Salary Salary: 67900 - 126100