Director, Clinical Pharmacology

Overview

Director, Clinical Pharmacology

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

We are currently seeking a Director, Clinical Pharmacology to join our diverse and dynamic team. As a Director, Clinical Pharmacology at ICON, you will play a pivotal role in leading the design, execution, and interpretation of early-phase clinical trial and clinical pharmacology programs to support the development of innovative therapies. You will ensure the strategic integration of pharmacokinetic and pharmacodynamic and safety data into clinical trial designs, driving informed decision-making and advancing therapeutic development.

Responsibilities

• Providing strategic leadership for first-in-human, early patient and clinical pharmacology studies, including risk assessment, pharmacokinetics, pharmacodynamics, and exposure–response modeling.
• Collaborating with cross-functional teams to integrate optimal clinical trial design and clinical pharmacology insights into clinical development programs and trial designs.
• Overseeing the analysis and interpretation of pharmacology data to inform dose selection, safety, and efficacy assessments.
• Providing strategic guidance on trial design and data analysis, with awareness of modeling and simulation techniques to optimize clinical trial designs and accelerate development timelines.
• Establishing and maintaining partnerships with internal and external stakeholders, including regulatory agencies and key opinion leaders, to ensure alignment on clinical pharmacology strategies.

Qualifications

• Advanced degree (PhD, PharmD, MD) in pharmacology, pharmaceutical sciences, or a related field.
• Significant industry experience in Clinical Pharmacology or Clinical PK/DMPK, or leadership roles in Clinical trial conduct within the pharmaceutical or biotechnology or CRO sectors.
• Extensive experience in clinical pharmacology, with a strong understanding of pharmacokinetics, pharmacodynamics, and modeling/simulation techniques.
• Strong leadership skills with a proven ability to manage cross-functional teams in a matrix environment.
• Expertise in data analysis and interpretation, with understanding or hands-on experience in pharmacokinetic software (e.g., NONMEM, WinNonlin) and statistical tools.
• Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive change in a complex organization.
• Experience working with regulatory authorities to ensure compliance and alignment on clinical pharmacology strategies.

What ICON can offer you

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Benefits

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply