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Associate Director, Global Supply Planning

Associate Director, Global Supply Planning

Orchard TherapeuticsLondon, England, GB
30+ days ago
Job type
  • Full-time
  • Quick Apply
Job description

Location :                      London, UK

Reporting to :                Vice President, Global Manufacturing Technology & Supply

Job Summary

The Associate Director, Global Supply Planning is responsible for end-to-end (E2E) supply planning activities for Orchard`s cell and gene therapy supply chain managing GMP plasmids, Vector Products (VP) and Drug Products (DP). This includes manufacturing planning at Orchard’s Contract Development and Manufacturing Organisations (CDMO’s) and ongoing management and control of Orchard’s GMP Inventory for Clinical and Commercial Operations. The job holder is part of the Global Manufacturing Technology & Supply leadership team, and will be expected to provide thought leadership on best supply planning practices supporting the overall Tech Ops strategic objectives.

Key Elements and Responsibilities

Supply Planning

  • Lead the Supply Planning process within Technical Operations for all programs and channel to operations addressing demand from Clinical, Medical and Commercial
  • Lead a cross functional Demand Planning Process
  • Generate supply and inventory planning across all of Orchard’s supply network and time horizons.

Inventory and Master Data Management

  • Develop the Material Requirements Planning (MRP) strategy,
  • Proactively manage obsolete inventory within the CDMO and 3rd party logistics (3PL) network
  • Manage 3rd party cold storage providers
  • Ensure master data accuracy
  • Lead the creation of inventory and storage policies in line with the latest GMP regulations.
  • Own and manage existing ERP system and support any future implementation of enterprise systems such as ERP and / or Advanced Planning Systems.
  • Manufacturing Planning and Execution

  • Ensure sufficient supplies of Clinical and Commercial Vector Product (VP) and capacity for Drug Product (DP) manufacturing
  • Manage CDMO GMP Supply Ordering and Delivery for Plasmids, VP and DP
  • Oversee the administration of all CDMO manufacturing financial transactions.
  • KPIs and Process Improvements

  • Define, monitor and strive to improve Key Performance Indicators to create a continuous improvement culture and collaborative planning environment
  • Identify and implement key supply chain related initiatives with internal stakeholders and external partners to improve supply chain efficiency.
  • Requirements

    Required Knowledge

  • At least 12 years of end-to-end supply chain experience with a minimum of 5 years of relevant biotechnology or pharmaceutical industry in roles across supply chain planning operations and external manufacturing in a global matrix
  • Relevant experience in cell & gene therapy and autologous ex-vivo gene therapy is ideal
  • Strong track record of effective team leadership, preferably in global organisations.
  • Proven experience in Demand / Supply Planning and Sales & Operations
  • Experienced in developing, implementing, and leading strategic initiatives which deliver change, continuous improvement and Operational Excellence to the business
  • Experience in managing and implementing supply chain systems across multiple areas of supply chain such as traditional ERP and SaaS technology
  • Strong Working knowledge of regulatory frameworks (FDA, EMA etc) GMP manufacturing and GMP storage requirements
  • Proven collaborative planning and relationship management experience in the biologics contract manufacturing or similar industry.
  • Skills & Abilities

  • Action-oriented and resourceful
  • Highly influential individual, able to navigate a complex landscape of stakeholders at all levels
  • Builds trusted partnerships and works collaboratively to meet shared objectives
  • Team-player as well as a highly supportive team lead with a continuous improvement coaching style and lead by example mentality
  • Resilient, works well under pressure and is able to prioritise and make robust decisions
  • Plans and prioritizing work to meet commitments aligned with organizational goals
  • Proven track record of achieving results.
  • Education

  • Minimum of bachelor’s degree in supply chain management, Life Sciences, Business Management or Engineering with relevant qualifications and experience in Supply Chain Operations and / or Operational Business Planning.
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    Associate Director Planning • London, England, GB

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