Location : London, UK
Reporting to : Vice President, Global Manufacturing Technology & Supply
Job Summary
The Associate Director, Global Supply Planning is responsible for end-to-end (E2E) supply planning activities for Orchard`s cell and gene therapy supply chain managing GMP plasmids, Vector Products (VP) and Drug Products (DP). This includes manufacturing planning at Orchard’s Contract Development and Manufacturing Organisations (CDMO’s) and ongoing management and control of Orchard’s GMP Inventory for Clinical and Commercial Operations. The job holder is part of the Global Manufacturing Technology & Supply leadership team, and will be expected to provide thought leadership on best supply planning practices supporting the overall Tech Ops strategic objectives.
Key Elements and Responsibilities
Supply Planning
- Lead the Supply Planning process within Technical Operations for all programs and channel to operations addressing demand from Clinical, Medical and Commercial
- Lead a cross functional Demand Planning Process
- Generate supply and inventory planning across all of Orchard’s supply network and time horizons.
Inventory and Master Data Management
Develop the Material Requirements Planning (MRP) strategy,Proactively manage obsolete inventory within the CDMO and 3rd party logistics (3PL) networkManage 3rd party cold storage providersEnsure master data accuracyLead the creation of inventory and storage policies in line with the latest GMP regulations.Own and manage existing ERP system and support any future implementation of enterprise systems such as ERP and / or Advanced Planning Systems.Manufacturing Planning and Execution
Ensure sufficient supplies of Clinical and Commercial Vector Product (VP) and capacity for Drug Product (DP) manufacturingManage CDMO GMP Supply Ordering and Delivery for Plasmids, VP and DPOversee the administration of all CDMO manufacturing financial transactions.KPIs and Process Improvements
Define, monitor and strive to improve Key Performance Indicators to create a continuous improvement culture and collaborative planning environmentIdentify and implement key supply chain related initiatives with internal stakeholders and external partners to improve supply chain efficiency.Requirements
Required Knowledge
At least 12 years of end-to-end supply chain experience with a minimum of 5 years of relevant biotechnology or pharmaceutical industry in roles across supply chain planning operations and external manufacturing in a global matrixRelevant experience in cell & gene therapy and autologous ex-vivo gene therapy is idealStrong track record of effective team leadership, preferably in global organisations.Proven experience in Demand / Supply Planning and Sales & OperationsExperienced in developing, implementing, and leading strategic initiatives which deliver change, continuous improvement and Operational Excellence to the businessExperience in managing and implementing supply chain systems across multiple areas of supply chain such as traditional ERP and SaaS technologyStrong Working knowledge of regulatory frameworks (FDA, EMA etc) GMP manufacturing and GMP storage requirementsProven collaborative planning and relationship management experience in the biologics contract manufacturing or similar industry.Skills & Abilities
Action-oriented and resourcefulHighly influential individual, able to navigate a complex landscape of stakeholders at all levelsBuilds trusted partnerships and works collaboratively to meet shared objectivesTeam-player as well as a highly supportive team lead with a continuous improvement coaching style and lead by example mentalityResilient, works well under pressure and is able to prioritise and make robust decisionsPlans and prioritizing work to meet commitments aligned with organizational goalsProven track record of achieving results.Education
Minimum of bachelor’s degree in supply chain management, Life Sciences, Business Management or Engineering with relevant qualifications and experience in Supply Chain Operations and / or Operational Business Planning.